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- The communication between the guts and the brain is influenced by a variety of neural, immune, endocrine, and humeral signals.
- How gut-derived peptides/hormones modulate neural circuits underlying energy homeostasis and cognitive function
The main types of dietary fibers which are essentially found in many fruits and vegetables is attracting more and more attention day by day as they provide numerous metabolic benefits to our body that results in moderating the weight of the body (Eikelenboom-Boskamp et al. 2019). The short-chain fatty acids (For E.g.: propionate and butyrate) which are produced through the process of fermentation occurring in the intestine region by the intestinal macrobiotic, was previously believed to be the main mediators of these beneficial aspects. In recent studies, the fatty acids, propionate, and butyrate were shown to activate the intestinal process of gluconeogenesis. Succinate, which is the precursor of propionate, found in the metabolism-related processes of bacteria, also exerts many kinds of signaling properties, which include the activation of the intestinal gluconeogenesis. The hormonal signals that the gut region of the body imposes to releases in blood in response to certain kinds of nutrient assimilations (Skidmore-Roth, 2019).